Abstract

A 5,6-dihydro-a-pyrone of formula (I) wherein R is CO 2 H or CH 3 and each of R<SP>1</SP> and R<SP>2</SP> is H; or R is CO 2 H, one of R<SP>1</SP> and R<SP>2</SP> is H and the other is OH; or when R is CO 2 H, a pharmaceutically or veterinarily acceptable salt thereof. Processes for producing compounds of formula (I) and their use as cytokine production inhibitors are also described.

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NO-Patent Citations (2)

    Title
    A.McKillop, J.Chem.Soc.Perkin Trans 1, 1996, 12, 1385-1392
    P.Wipf et al, J.Org.Chem, 1993, 58(25), 7195-7203

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